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Prism
Powered by the Brain.

An interventional psychiatry suite of treatments and solutions powered by
fMRI-informed digital biomarkers for personalized patient care. 

GrayMatters Health is leading a transformation - bringing evidence-based digital biomarker technology to psychiatry clinics to augment standard-of-care therapies and help improve patient outcomes and patient lives.

 

With a strong foundation in scientific research, Prism self-neuromodulation is being used to help patients learn to regulate brain activity associated with their mental health condition in the clinic, gaining a skill for use in their daily lives.  

 

Prism is a comprehensive suite of solutions for scientifically leveraging the power of the brain, featuring protocols for PTSD and Depression. Learn more >> 

 

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Prism™ Imagine. Selfie of the mind™.

GrayMatters Health introduces a new way to connect with your patients in their daily life. Learn more >>

Leading-edge technology

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The ground-breaking fMRI-Informed digital biomarkers that power Prism have a strong scientific and clinical foundation. The PTSD protocol uses an amygdala-based biomarker and the Depression protocol uses a reward-system biomarker. Learn more about our biomarkers >>

Operational simplicity​

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Prism integrates seamlessly with operational flow from intake to treatment. All you need is a quiet room, table and chair and a trained Prism Operator. Read a Case Study of a Community Clinic in Texas.

Personalized care​

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At the core of Prism is the mental strategy. Each patient explores which personal memory, emotion or experience gets the animated characters in the Prism simulation to respond. A mental strategy is as personal as it gets!​​​​​​​

With you every step of the way

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A dedicated Account Manager will be your co-pilot to help build a Prism service at your practice. Ask about our Prism Pathway to guide you.

 

 

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Impact on
Patients

"Since using Prism, my quality of life has improved and my capacity to enjoy life has really opened up! I feel calmer, more in control, and am thinking more clearly.”
Prism Patient​

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© 2026 GrayMatters Health. All Rights Reserved.

Disclaimer: The information on this website is not intended to be a substitute for professional medical advice. Always discuss treatment options and treatment outcomes with your physician or other qualified mental health provider.​

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