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Prism™ for PTSD

Prism™ by GrayMatters Health is an evidence-based, prescription therapy, FDA-cleared to treat PTSD.  During Prism sessions, a computer simulation and soft EEG cap create an environment where patients engage in a non-trauma-based experience to help them learn to control their PTSD symptoms.   

Prism is the first PTSD treatment based on a digital fMRI-Informed biomarker associated with mental health disorders.  Read more about the technology behind Prism for PTSD.   

PRISM REGIMEN

15 sessions, over 8 weeks or
as determined by healthcare provider.
Booster sessions as needed.
Each session lasts about 45 minutes. 
PROVEN CLINICAL OUTCOMES

Clinical studies and real-world experience have demonstrated significant improvement in PTSD symptoms with a high safety profile. 

OPERATIONAL SIMPLICITY

All you need is a quiet room, table, chair and trained Prism Operator. Read a Case Study of a Community Clinic in Texas. 

PERSONALIZED CARE

Patients explore mental strategies - a personal memory, emotion or experience - that gets the animated characters in the Prism simulation to
sit down and lower their voices. 

YOUR PARTNER

A dedicated GrayMatters Health Account Manager will be your co-pilot to help build a Prism service at your Interventional Psychiatry practice.

The Prism for PTSD multi-center clinical study demonstrated the following results

3 months after the 15-session regimen (5 months from baseline): 

  • 67% of patients overall demonstrated clinically significant symptom improvement
    as measured by CAPS-5. 

  • Significant improvement in sleep, as measured by PHQ-9 and CAPS-5. 

  • 32% of patients experienced remission.  

  • 90% patient compliance. 

  • Mild side effects, such as fatigue and headache, resolved after treatment
    with no further intervention. 

Fruchter et al. Psychiatry Research 333 (2024), 115711.

Clinical
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© 2026 GrayMatters Health. All Rights Reserved.

Disclaimer: The information on this website is not intended to be a substitute for professional medical advice. Always discuss treatment options and treatment outcomes with your physician or other qualified mental health provider.​

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